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Biomedical

Fluorescence Microscopy

The discovery of fluorescent proteins and the use of fluorescent probes have led to the widespread acceptance of fluorescence microscopy and imaging in biological and materials sciences. Lasers are the most common light sources in fluorescence microscopy and are used to excite fluorescent probes, which in turn emit fluorescent signals that identify and characterize particular molecules.

Imaged by fluorescence microscopy using DAPI stain, which is excited by ultraviolet light

Laser beam stability is extremely important because illumination intensity fluctuations can adversely affect experimental results. Lasiris™ TEC lasers are available in a wide range of wavelengths (including 404, 440, and 473 nm) and are customizable to meet your stringent microscopy requirements. Our design boasts long diode lifetimes, superior beam quality, and stable laser output, ensuring that you get the most out of your illumination source.

Bio-Detection & Analysis

When used in conjunction with StockerYale's refractive beam shaper, the Flat-Top² Generator, our structured light lasers can illuminate a rectangular or square shaped area with uniform intensity for use in bio-detection and other biomedical applications where scanning or inspection of biological molecules over a given area is necessary. New developments in the photonics field and the increase in demand for biological agent identification systems have created a new need for efficient and reliable illumination sources for such applications.

Flow Cytometry

Flow cytometry is a technique for characterizing (i.e. counting, examining, sorting) microscopic molecules and cells. It allows users to analyze the physical and biochemical attributes of particles that pass through a detection apparatus. In order to do so, laser light is directed onto flowing liquid that contains the targeted molecules. Each particle that comes in contact with the laser beam scatters light in a particular way and this data provides valuable information to the user about cell size and shape, cell content, etc.

Lasiris™ line lasers and the Flat-Top² Generator are ideal solutions for flow cytometry applications as we offer robust, high power lasers with uniform lines for high-speed particle analysis. Line uniformity is particularly important in order to ensure that all particles that hit any point on the line are measured in a consistent fashion. In addition, our line lasers are available in a multiple wavelengths for experiments involving fluorescent probes that are excited at particular wavelengths.

Visit our structured light lasers page for more information on our product offerings.